Reactivity of C=C C—C Electrons in pi bond are loosely held Electrophiles are attracted to the pi electrons. · Carbocation intermediate forms. Nucleophile adds to the carbocation. · Net result is addition to the double bond

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Classes of Halides Alkyl: Halogen, X, is directly bonded to sp3 carbon. Vinyl: X is bonded to sp2 carbon of alkene. Aryl: is bonded to sp2 carbon on benzene ring. Examples:

A basic knowledge of disinfection and sterilization is crucial for biosafety in the laboratory. Since heavily soiled items cannot promptly be disinfected or sterilized, it is equally important to understand the fundamentals of cleaning prior to disinfection (precleaning). In this regard, the following general principles apply to all known classes of microbial pathogens

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The reasonable person adapts himself to the world while the unreasonable one persists in trying to adapt he world to himse!.” George bernard Shaw

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连续时间马氏链 仍记状态空间为S={0,1,2,…} 定义设随机过程X={X(t),t≥0}对于任意0≤to0就有 P{(tn+1)=in+1(to) io, X (t1) =i1,.,()= in} =P{X(tn+) in+()= in} 则称{X(t),t≥0}为连续参数马尔可夫链(简称连续参数马氏链)

Introduction to Manufacturing a Manufacturing is the physica/ realization of the previously designed parts Metrics to assess the\ performance\of mfg Quality does it meet specifications?