一、细胞生物学研究的内容和现状 二、细胞生物学是现代生命科学的重要基础学科 三、细胞生物学的主要研究内容 四、当前细胞生物学研究的总趋势与重点领域 五、细胞重大生命活动的相互关系

一、名词解释 1.-s细胞(Reed-Sternberg cell) 答案:①一种体积大的双核关或多核关瘤巨细胞;②瘤细胞胞质丰富;③细胞核呈双 叶或多叶状,状似双核或多核细胞;④大嗜酸性核仁,周围有空晕

General introduction Ion channels G-protein coupled receptors Second messengers Tyrosine kinase receptors From plasma membrane to the nucleus: Regulation of gene expression Cytokine signaling Cell cycle Apoptosis

Figure 2 in Muratani M, Tansey WP. \How the ubiquitin-proteasome system controls transcription.\ Nat Rev Mol Cell Biol. 2003 Mar; 4(3): 192-201. Regulation of TCR by ubiquitylation of RNA polymerase II. Transcription-coupled repair (TCR)is the mechanism through which mutations in actively transcribed genes are preferentially repaired. a Elongating RNA polymerase II (pol II)

biologically active model of ECM acts as an insoluble regulator of cell function image removed due to copyright considerations

The Extracellular Matrices Part. 2. Elastin fibers. 3. Proteoglycans(PG) and glycosaminoglycans (GAG). 4. Cell-adhesion molecules (CAM)

The Cell and Its Membrane Molecules Plasma membrane-5nm Rough ER Smooth ER Nucleus-3-10 um Nucleolus Nuclear pore -Golgi complex Extracellular

Introduction. Chapter 1. Irreversible Healing of Extracellular Matrix. Chapter 2. Cell-Matrix Interactions. Chapter 3. Synthesis of Tissues and Organs. TEXT: I. V. Yannas. Tissue and Organ Regeneration in Adults. New York: Springer, 2001

How does it work? Ofloxacin belongs to a group of broad spectrum antibiotics called the quinolones. It works by entering the bacterial cell and inhibiting a chemical called DNA-gyrase which is involved in the production of genetic material (DNA). This therefore prevents the bacteria from reproducing

Reversible ligation of Ubiquitin and Ubls to other proteins. Figure by MIT OCW. After Figure 1 in Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000 Aug: