As aerosols are important sources of infection, care should be taken to reduce the extent of their formation and dispersion Hazardous aerosols can be generated by many laboratory operations, e.g. blending, mixing, grinding, shaking, stirring, sonicating and centrifuging of infectious materials. Even when safe equipment is used, it is best to carry out these operations in an approved biological safety cabinet whenever possible
Laboratory/facility commissioning may be defined as the systematic review and documentation process signifying that specified laboratory structural components, systems and/or system components have been installed, inspected, functionally tested and verified to meet national or international standards, as appropriate
The containment laboratory Biosafety Level 3 is designed and provided for work with Risk group 3 microorganisms and with large volumes or high concentrations of risk group 2 microorganisms that pose an increased risk of aerosol spread