筛选途径需要解决的基本问题 I. 结构多样性(Diversity) II. 转化医学(Translational Medicine, from bench to bedside) 合成化合物的筛选 组合化学、多样性导向合成及片段库 转化医学 (Translational Medicine, from bench to bedside, from bed to bench) Neoclassic drug discovery 新经典药物发现 —— Phenotypic Screening
1. Hemoglobin is a multisubunit allosteric rotein that carries 02 in erythrocyte. 1.1 Hemoglobin is a well-studied and well-understood protein. 1.1.1 It was one of the first proteins to have its molecular mass accurately determined. 1.1.2 The first protein to be characterized by ultracentrifuge. 1.1.3 The first protein to be associated with a specific physiological function
7-1 Introduction to the Activated-Sludge Process Historical Development The activated-sludge p now used routinely for biological treatment of municipal and industrial dge process date back to the early 1880s to the work of stewater in tanks and the hastening of the oxidation quently by a number of investigators, ility could be secured by e Experiment Station
Strategic Human Resource Management SHRM is the linking of HRM with strategic goals and objectives in order to improve business performance and develop organizational cultures that foster innovation and flexibility. SHRM is the pattern of planned human resource deployment and activities intended to enable an organization to achieve its goals
Chapter 14 Topics Structured Programming vS Object-Oriented Programming Using Inheritance to Create a New C++ class Type Using Composition( Containment) to Create a New C++ class Type Static vs Dynamic Binding of Operations to Objects
Slide 15.6.1 The next stage in the evolution of our evaluator is to pull the 5. Environment as explicit parameter environment out as an explicit parameter. Up until now we could rely on just having a single environment in which to store (eva1'(pus*64)) bindings for variables. It made sense to have a global
The Significance of Breeding for Resistance to Diseases and Insect Pests抗病虫育种的意义 1. Resistance of Crops to Diseases and Insect Pests (1) Disease and pest damages are popular in Crop Production
text B. detailed study of the text 1. on the move: moving from place to place e.g. It's hard to contact her---she's al ways on the move The Johnsons are on the move from the city to the country