Summarization Definition: serum total bilirubin (STB) > 34µmol/L, causing a yellow color of skin, sclera and tissue fluid Latent icterus: an increase of STB but not more than 34µmol/L, without color changes of skin and sclera False jaundice: yellow skin and sclera but without hyperbilirubinemia, due to ingestion of some drugs and foods

General Considerations Disorders of hemostasis defects in platelet number or function problems in fibrin clot (coagulation) Bleeding due to platelet disorders is typically mucosal or dermatologic include epistaxis, gum bleeding, menorrhagia, gastrointestinal bleeding, purpura, and petechiae

一. Types of lupus Discoid Systemic Drug-induced

定义 除心脏瓣膜病、冠心病、高血压心脏病、肺心病和先心以外，以心肌病变为主要表现的一组疾病

Overview Clinical syndrome Slowing down of metabolism Slowing of growth and mental retardation in infants and children Generalized slowing down of organism Deposition of glycosaminoglycans in skin and muscle Reversible with therapy

Cirrhosis---definition chronic, progressed, diffuse hepatocellular injury fibrosis nodular regeneration

Key Words Respiratory failure Acute respiratory distress syndrome(ARDS) dyspnea Hypoxemia hypercapnia Respiratory Support

Cardiovascular disease Cerebrovascular diseases Lower respiratory infections Diarrhea Perinatal disease COPD Tuberculosis Morbilli

Chapter three Chronic Obstructive Pulmonary Diseases (COPD) Chronic Bronchitis Obstructive Pulmonary Emphysema

Concept of leukemia Definition It is the results of the tumor proliferation of heamotopoietic stem cells.（造血干细胞） Leukemia is a malignant blood disorder. (not solid tumor)