Choosing an Animal Model Pathogen may not affect animal at all -ORmay give different symptoms Given disease may have a number of animal models, none of which fully satisfies characteristics of disease
General aspects – Remember definition: organisms frequently found on or within body of healthy individuals – Most are bacteria, but some are viruses, fungi, and protozoa
Microbial pathogenesis—process of causing disease Colonization—presence of microbes at site of body – Does not imply tissue damage or disease symptoms – Does imply invasion of site and multiplication