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Allylic 1-3-Strain as a Controlling Element in Stereoselective Transformations TSO(2C)4 R. W. Hoffmann, Angew. Chem. Int. Ed. Engl. 2000, 39, 2054-2070 CH2)lOTs Conformation Design of Open-Chain Compounds
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Hyperconjugation and \Negative\ Hyperconjugation Anomeric and Related Effects An Introduction to Frontier Molecular Orbital Theory-1 Problem of the Day The molecule illustrated below can react through either Path A or Path B to form salt 1 or salt 2 . In both instances the carbonyl oxygen functions as the
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Stereoelectronic Effects-1 Anomeric and Related Effects Electrophilic & Nucleophilic Substitution Reactions The SN2 Reaction: Stereoelectronic Effects Olefin Epoxidation: Stereoelectronic Effects Baeyer-Villiger Reaction: Stereoelectronic Effects Olefin Bromination: Stereoelectronic Effects
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Prelog Strain: van der Waals interactions Baeyer Strain: bond angle distortion away from the ideal Pitzer Strain: torsional rotation about a sigma bond Baeyer Strain for selected ring sizes size of ring Ht of Combustion
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Theory & Modeling of Stereoselective Organic Reactions (Handout) Epoxidation & Directed Epoxidation Hydrogenation Hydride Reduction
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Carey& Sundberg, Part A, CH 4, pp 187-250 Conformational Analysis-4 a Problems of the Day:(To be discussed) Conformational Analysis of C6 >Cg Rings continued Predict the stereochemical outcome of this reaction
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Classification of Functional Groups Each substituent attached to carbon activates that carbon toward a polar reaction by either resonance or induction or both. Induction
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Recent Applications of the Prins Reaction in Stereoselective Synthesis Matthew D. Shair Monday
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Angew. Chem. Int Ed. 2000, 39, 2812-2833 \That outpost of empire Australia, produces some curious mammalia, the kangaroo rat, the blood-sucking bat, and Aurthur J. Birch, inter alia.\ If you are anxious for over-exposure, to prepublication disclosure, to good food and good drink
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Here is a typical carbonium ion question that you should be able to handle by the end of the course. Write out a mechanism for the following transformation
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