 Definition  The Pathogen  Epidemiology  Etiology and Life Cycle  Pathobiology  Clinical manifestations  Diagnosis  Treatment

 Gram-negative, obligate intracellular coccobacilli bacteria that infect mammaols and arthropods  Rickettsiae are transmitted in the arthropods,which serves as both vector and reservior  Both DNA and RNA  Is sensitive to antibiotic  Culture：in animate media

复旦大学：《传染病学 Infectious diseases》课程教学资源（课件讲稿）布鲁氏菌病 Brucellosis

⚫ Normal body temperature: 37oC (set point) Circadian variation oral T 0. 4oC > axillary T ⚫ Definition of fever: An elevation of core body temperature above the normal range

• Diarrheal illness is one of the leading causes of death worldwide. • It is most commonly encountered in develeoping countries. • Can be life-threatening in infants, young children, and elderly people. Most individuals with this illness can be managed as outpatients

影响流行过程的因素主要是通过对传染源、传播途径和易感动物的影响作用而发生的。主要有:

定义、病原菌、发病机制、临床表现、实验室检查、诊断与鉴别诊断、预后、治疗

复旦大学：《传染病学 Infectious diseases》课程教学资源（讲义）菌痢与霍乱（细菌性痢疾）

1、脊髓灰质炎是由脊髓灰质炎病毒引起的急性传染病 、脊髓灰质炎是由脊髓灰质炎病毒引起的急性传染病。 2、临床表现为发热、咽痛及肢体疼痛，部分发生肢体弛缓性瘫。严重病人因呼吸麻痹而死亡 。严重病人因呼吸麻痹而死亡。 3、多发生于小儿 、多发生于小儿，故俗称“小儿麻痹症

一、流行过程的表现形式: 二、散发性 三、地方流行型