One complication associated with alkene hydration is the occurrence of arrangements

Acetylenic hydrogens can be deprotonated with relatively strong bases (sodium amide is typical)

Alkenes are hydrocarbons whose molecules contain the carbon-carbon double bond. Alkynes are hydrocarbons whose molecules contain the carbon-carbon triple bond

Infrared Spectroscopy: An Instrumental Method for detecting Functional Groups

Substitution reactions occur when two reactants exchange parts to give two new products. In a substitution, one replaces another

21.11 Aryl Halide and Nucleophilic Aromatic Substitution 21.12 Spectroscopic Analysis of Phenols and Aryl Halides

17.7 Lithium Enolates 17.8 α-Selenation: A Synthesis of α,β-Unsaturated Carbonyl Compounds 17.9 Additions to α,β-Unsaturated Aldehydes and Ketones

If a chiral atom attached to the carbonyl group, the stereoselectivity of nucleophilic addition follows the Cram’s rule

Many other pairs of reagents that form cabocations (orcarbocationlike species) may be used as well

No addition of bromine No oxidation No hydroation Slow addition at high temperature and pressure