Theory & Modeling of Stereoselective Organic Reactions (Handout) Epoxidation & Directed Epoxidation Hydrogenation Hydride Reduction

Smith, K. and A. Pelter (1991). Hydroboration of C=C and Alkynes. Comprehensive Organic Synthesis. B. M. Trost and I. Fleming. Oxford, Pergamon Press. 8: 703. Beletskaya, I. and A. Pelter (1997). “Hydroborations catalysed by transition metal complexes

Carey& Sundberg, Part A, CH 4, pp 187-250 Conformational Analysis-4 a Problems of the Day:(To be discussed) Conformational Analysis of C6 >Cg Rings continued Predict the stereochemical outcome of this reaction

Evans Group Seminar, February 13, 1998 For a recent general review of the Simmons-Smith reaction see:

Classification of Functional Groups Each substituent attached to carbon activates that carbon toward a polar reaction by either resonance or induction or both. Induction

Isolated from bark and leaves of Yuzuriha tree Used to cure asthma and vermicide in the early 20th century Compounds have been known since 1909. First structure solved in 1965

Recent Applications of the Prins Reaction in Stereoselective Synthesis Matthew D. Shair Monday

The Aza-Cope Rearrangement. Background and Application to Alkaloid Synthesis Mike calter Evans group seminar

The product-determining step could be step A NabH3CN Rc R Meo Me Matthew d shair

Here is a typical carbonium ion question that you should be able to handle by the end of the course. Write out a mechanism for the following transformation