5.Gabriel合成法 R R NK'X-CHCOOC2Hs-KX -CHCOOC2H5 COOH H2N-CHCOOH+C2H5OH H,H20 COOH NK* +BrCH(COOC2Hs)2 NCH(COOC2Hs)2 0 (1)C2HgONa NCH(COOC2Hs)2 (1)H0,H20 H2NC HCOOH (2)R-X R 2)H,△ R 99 BrCH(COO C2H5)2 C C O O K + + N￾C C O O NC H(CO OC 2H5)2 (2) (1) C2H5O Na R X NC H(CO OC 2H5)2 R C C O O (1) (2) HO - H2O H + , , H2NC HC OOH R Δ 5．Gabriel合成法 C C O O - NK+ + X CHCOOC2H5 R _ KX N CHCOOC2H5 C R C O O H+ , H2O COOH COOH + H2N CHCOOH + R C2H5OH