Myeloma proteins If we are going to study the structure of antibodies they must be purified and antibodies are difficult to purify since they have the same chemical and physical properties.One way around the purification problem is to use myeloma proteins which can be obtained in pure form from multiple myeloma patients. Plasma cells normally form one specific kind of antibody in relatively small quantities.It was observed that plasma cells can be transformed into tumor plasma cells,called myeloma cells.The transformed cells produce monoclonal antibodies of a single type since each tumor consist of identical cells.The antibodies may be in the form of an intact globulin,light chain peptide or heavy chain peptide. s of cells which 4C entibody released dentical Antibody(IgG) Myeloma Proteins If we are going to study the structure of antibodies they must be purified and antibodies are difficult to purify since they have the same chemical and physical properties. One way around the purification problem is to use myeloma proteins which can be obtained in pure form from multiple myeloma patients. Plasma cells normally form one specific kind of antibody in relatively small quantities. It was observed that plasma cells can be transformed into tumor plasma cells, called myeloma cells. The transformed cells produce monoclonal antibodies of a single type since each tumor consist of identical cells. The antibodies may be in the form of an intact globulin, light chain peptide or heavy chain peptide