Dendritic cell therapies include the use of antibodies that bind to receptors on the surface of dendritic cells T6nmdm出e Sipuleucel-T nting cells from blood by leukapheresis and growing them with the fusion protein PA2024 高9 po Antibody therapy ibrboin oad playing a centr 八慧要 against specific antigens,such as those present on tumor surfaces. ”电 Antibody types Many forms of antibodies can be Conjugation Two typesare used in cancer treatments:4] Nakdnbdiesreibdehouadded elemeMost aibody therapesusehis Conjugated monoconaantibodies are joined to another moleue which is either cytotoxicor radioa tive. chemicals are tho e typically used as chemotherapy drugs,but other can be d-linked antbo immunotoxins antibodies are tagged with chemotherapeutic molecules or toxins,respectively.5 Human/non-human balance ,chimeric,humanized and human.Murine antibodies are from of th meric andin bodies rine aas the constant region.Humanized antibodies are almost completely human:only the complementarity determining o the varlable regions are derived fom mrine sources.Human antbodes have compleely human Cell death mechanisms Antibody-dependent cell-mediated cytotoxicity(ADCC) Antibody-dependent cell-mediated cytotoxicity (ADCC)reguires antibodies to bind to target cell surfaces. Antibodies are formed of a binding region(Fab)and the Fc region that can be detected by immune system cells pto und on many immun sys m c yme B to kill the or cell.E umab