42卷5期 曹胜男等：α-环糊精戊酸包合物的制备及释放动力学研究 705 由块状变为片状：包合物出现戊酸的特征峰且无新 [刀冯江涛，延卫，徐浩，等.1甲基环丙烯与-环糊精包 的吸收峰出现，表明丁酸乙酯与环糊精发生包合但 合物的合成).应用化学，2010,27(1)少82-86. 没有发生化学反应：XRD衍射峰的改变证明环糊精 [8]Kiruba K,Valetie O,Thangavel K.Synthesis and charac- terization of nano-encapsulated catechin by molecular in- 由晶体向无序状态变化：核磁共振波普显示α-环糊 clusion with beta-cyclodextrin[J].Journal of Food Engi- 精在包合戊酸后空间结构更加对称。 neering.2012.111:255-264. 33环糊精包合物的释放特性 [9]Wang J.Cao Y.Sun B,et al.Physicochemical and release characterization of garlic oil-B-cyclodextrin inclusion 湿度越大，戊酸释放越快：温度越高，释放速 complexes[J].Food Chemistry,2011,127:1680-1685. 率越快，说明α-环糊精戊酸包合物的贮藏应选取低 [10]金征宇，徐学明，陈寒青，等.环糊精化学一制备与 温干燥的条件。 应用M.北京：化学工业出版社，2009：3-8 [11]Onanong N,Somsak S,Issara S,et al.Physicochemical 参考文献： investigation and molecular modeling of cyclodextrin complexation mechanism with eugenol[J].Food Research [1]马云标，周惠明宰，朱科学.VE微胶囊的制备及性质研 International,2009,42:1178-1185. 究.食品科学，201031(2)：1-4. [12]Jiang H M,Sun H J,Zhang S B.NMR investigations of [2]Okumura H,Kawaguchi Y and Harada A.Preparation and inclusion complexes between beta-cyclodextrin and characterization of the inclusion complexes of poly (di- naphthalene/anthraquinone derivatives[J].Journal of In- methylsilane)s with cyclodextrins[J.Macromolecules, clusion Phenomena and Macrocyclic Chemistry,2007, 2003,36:6422-6429 58(1/2):133-138. [3]Szejtli J.Selectivity/structure correlation in cyclodextrin [13]Ge X,He J,Qi F,et al.Inclusion complexation of chloro- chemistry[J].Supramolecular Chemistry,1995(6):217-223. propham with B-cyclodextrins:Preparation,characteriza- [4)]周春晖，黄惠华.环糊精性质及其在食品工业中应用 tion and molecular modeling[J.Spectrochimica Acta Part J.粮食与油脂，2000(5)：30-32. A:Molecular and Biomolecular Sptctroscopy,2011,81: [S]张扬，周裔彬，曹胜男，等.B和Y-环糊精与丁酸乙酯包 397-403. 合物的制备及结构表征).食品与发酵工业，2014(9)： [14]Seo E J,Min S G and Choi M J.Release characteristics of freeze-dried eugenol encapsulated with B-cyclodextrin by 34-38 molecular inclusion method []Journal of Microencapsu- [6]邓靖，谭兴和，刘婷婷，等.肉桂精油-阝环糊精微胶囊 lation,2010:27(6:496-505. 的制备).中国粮油学报，2011,26(2)：89-91,97.42 卷 5 期 曹胜男等: α-环糊精戊酸包合物的制备及释放动力学研究 705 由块状变为片状；包合物出现戊酸的特征峰且无新 的吸收峰出现，表明丁酸乙酯与环糊精发生包合但 没有发生化学反应；XRD 衍射峰的改变证明环糊精 由晶体向无序状态变化；核磁共振波普显示 α-环糊 精在包合戊酸后空间结构更加对称。 3.3 环糊精包合物的释放特性 湿度越大，戊酸释放越快；温度越高，释放速 率越快，说明 α-环糊精戊酸包合物的贮藏应选取低 温干燥的条件。 参考文献： [1] 马云标, 周惠明宰, 朱科学. VE 微胶囊的制备及性质研 究[J]. 食品科学, 2010, 31(2): 1-4. [2] Okumura H, Kawaguchi Y and Harada A. Preparation and characterization of the inclusion complexes of poly (di￾methylsilane)s with cyclodextrins[J]. Macromolecules, 2003, 36: 6422-6429. [3] Szejtli J. Selectivity/structure correlation in cyclodextrin chemistry[J]. Supramolecular Chemistry, 1995(6): 217- 223. [4] 周春晖, 黄惠华. 环糊精性质及其在食品工业中应用 [J]. 粮食与油脂, 2000(5): 30-32. [5] 张扬, 周裔彬, 曹胜男, 等. β-和γ-环糊精与丁酸乙酯包 合物的制备及结构表征[J]. 食品与发酵工业, 2014(9): 34-38. [6] 邓靖, 谭兴和, 刘婷婷, 等. 肉桂精油-β-环糊精微胶囊 的制备[J]. 中国粮油学报, 2011, 26(2): 89-91; 97. [7] 冯江涛, 延卫, 徐浩, 等. 1-甲基环丙烯与 α-环糊精包 合物的合成[J]. 应用化学, 2010, 27(1): 82-86. [8] Kiruba K, Valetie O, Thangavel K. Synthesis and charac￾terization of nano-encapsulated catechin by molecular in￾clusion with beta-cyclodextrin[J]. Journal of Food Engi￾neering, 2012, 111: 255-264. [9] Wang J, Cao Y, Sun B, et al. Physicochemical and release characterization of garlic oil-β-cyclodextrin inclusion complexes[J].Food Chemistry, 2011, 127: 1680-1685. [10] 金征宇, 徐学明, 陈寒青, 等. 环糊精化学——制备与 应用[M]. 北京: 化学工业出版社, 2009: 3-8. [11] Onanong N, Somsak S, Issara S, et al. Physicochemical investigation and molecular modeling of cyclodextrin complexation mechanism with eugenol[J]. Food Research International, 2009, 42: 1178-1185. [12] Jiang H M, Sun H J, Zhang S B. NMR investigations of inclusion complexes between beta-cyclodextrin and naphthalene/anthraquinone derivatives[J]. Journal of In￾clusion Phenomena and Macrocyclic Chemistry, 2007, 58(1/2): 133-138. [13] Ge X, He J, Qi F, et al. Inclusion complexation of chloro￾propham with β-cyclodextrins: Preparation, characteriza￾tion and molecular modeling[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Sptctroscopy, 2011, 81: 397-403. [14] Seo E J, Min S G and Choi M J. Release characteristics of freeze-dried eugenol encapsulated with β-cyclodextrin by molecular inclusion method [J].Journal of Microencapsu￾lation, 2010; 27(6): 496-505