LETTER RESEARCHLetter RESEARCH Extended Data Figure 7 | Comparison of dihydropyridine binding site in CaVAb and CaV1.2. The pore domain of CaVAb is illustrated with two subunits in view, one in tan corresponding to domain III of CaV1.2 and one in blue corresponding to domain IV of CaV1.2. The amino acid residues in CaVAb corresponding to those that are important for dihydropyridine binding to CaV1.2 channels are highlighted in red. Bound amlodipine is illustrated with green sticks. © 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved