6、 Clinica| Features ncubation period: Average 60-90 days Range 45-180 days Insidious onset of symptoms Tends to cause a more severe disease than hepatitis a Clinical illness jaundice) <5yrs2410% ≥5yrs,30%50% 1/3 adults-no symptoms Clinical Ilness at presentation 10-15% Acute case-fatality rate 0.5%-1% Chronic infection: <5yrs,30%-90% ≥5yrs,2%-10% More likely in asymptomatic infections Premature mortality from chronic liver disease 15%-25%6、Clinical Features Incubation period: Average 60-90 days Range 45-180 days Insidious onset of symptoms. Tends to cause a more severe disease than Hepatitis A. Clinical illness (jaundice): <5 yrs, <10% ≥ 5 yrs, 30%-50% 1/3 adults-no symptoms Clinical Illness at presentation 10 - 15% Acute case-fatality rate: 0.5%-1% Chronic infection: < 5 yrs, 30%-90% ≥ 5 yrs, 2%-10% More likely in ansymptomatic infections Premature mortality from chronic liver disease: 15%-25%