Guide treatment according to laboratory sensitivities rather than choosing an Treatment antibiotic empirically Widespread resistance to many common 应加强医用仪器的消毒,防止医源 first-line antibiotics>carbapenems 性感染;同时应注意医务人员与患 者及患者间的交叉感染。可选用氨 polymyxins and more recently tigecycline 基糖苷类和β-内酰胺类抗生素联合治 considered to be the drugs of choice 疗 B-lactamase inhibitors such as sulbactam in 《医学微生物学》P170 combination with antibiotics> enhance antimicrobial action even in the presence of a certain level of resistance Combination therapy after rigorous antimicrobial susceptibility testing has been found to be the best course of action in the treatment of multidrug-resistant P aerugInosa. Some next-generation antibiotics are active against P aeruginosa include doripenem ceftobiprole, and ceftaroline. need more clinical trials)Treatment • Guide treatment according to laboratory sensitivities rather than choosing an antibiotic empirically. • Widespread resistance to many common first-line antibiotics → carbapenems, polymyxins and more recently tigecycline considered to be the drugs of choice. • β-lactamase inhibitors such as sulbactam in combination with antibiotics → enhance antimicrobial action even in the presence of a certain level of resistance. • Combination therapy after rigorous antimicrobial susceptibility testing has been found to be the best course of action in the treatment of multidrug-resistant P. aeruginosa. • Some next-generation antibiotics are active against P. aeruginosa include doripenem, ceftobiprole, and ceftaroline.(need more clinical trials) 应加强医用仪器的消毒，防止医源 性感染；同时应注意医务人员与患 者及患者间的交叉感染。可选用氨 基糖苷类和β-内酰胺类抗生素联合治 疗。 ——《医学微生物学》P170