Fudan University Cancer Center rimary tumor localized intravasation transport arrest in extravasation ormation Invasion through microvessels of circulation various organs 解-B interaction with platelets, lymphocytes, and other blood formation of a components micrometastasis Tumor metastasis is a complex, multistep process consisting of a colonization formation of a series of discrete biological macrometastasis processes. Figure 14.4 The Biology of Cancer(@ Garland Scie nce 2007)p 591 复旦大学上海医学院肿瘤学系复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Figure 14.4 The Biology of Cancer (© Garland Science 2007) p. 591 Tumor metastasis is a complex, multistep process consisting of a series of discrete biological processes