IgE Levels in Disease Normal levels do not preclude atopy 30%of random population allergic to at least one common allergen Genetic background puts individual at risk family history indicates predisposition for atopy cannot predict specific reactions(s) higher level of IgE associated with increased risk of atopy IgE Levels in Disease ◼ Normal levels do not preclude atopy ◼ 30% of random population allergic to at least one common allergen ◼ Genetic background puts individual at risk ◼ family history indicates predisposition for atopy ◼ cannot predict specific reactions(s) ◼ higher level of IgE associated with increased risk of atopy