Continued ● Other responses -Immune responses -local anaesthesia Temporary desensitization of nerves(0C~-5C) Hours or days of recovery time (-5C~-15C) Long term desensitization (colder than-15C) -Wound healing Collagen fibers and fibroblasts resistance to damage after freezing Vessel structure almost intact Bone structure well maintainedContinued • Other responses – Immune responses – local anaesthesia • Temporary desensitization of nerves( 0oC~‐5oC) • Hours or days of recovery time (‐5oC~ ‐15oC） • Long term desensitization (colder than ‐15oC) – Wound healing • Collagen fibers and fibroblasts resistance to damage after freezing • Vessel structure almost intact • Bone structure well maintained