Adults Symptoms t Easy fatigability t Coldness Weight gain Constipation t Menstrual irregularities Signs Cool, rough, dry skin t Puffy face and hands t Hoarse and husky voice t slow reflexes t Yellowish color skinAdults Symptoms  Easy fatigability  Coldness  Weight gain  Constipation  Menstrual irregularities Signs  Cool, rough, dry skin  Puffy face and hands  Hoarse and husky voice  Slow reflexes  Yellowish color skin