CHARACTERISTICS OF CORONAVIRUS DISEASE 2019 IN CHINA 原目销身厚月自里 ~期目 日。 星果839目 用围 。 买 N ENGLJ MED NEJM.ORG The New England Joumal of Medicine onal use only.No other uses without permission n engl j med nejm.org 7 Char acteristics of Coronavirus Disease 2019 in China Symptoms — no. (%) Conjunctival congestion 9 (0.8) 5 (0.5) 4 (2.3) 0 9 (0.9) Nasal congestion 53 (4.8) 47 (5.1) 6 (3.5) 2 (3.0) 51 (4.9) Headache 150 (13.6) 124 (13.4) 26 (15.0) 8 (11.9) 142 (13.8) Cough 745 (67.8) 623 (67.3) 122 (70.5) 46 (68.7) 699 (67.7) Sore throat 153 (13.9) 130 (14.0) 23 (13.3) 6 (9.0) 147 (14.2) Sputum production 370 (33.7) 309 (33.4) 61 (35.3) 20 (29.9) 350 (33.9) Fatigue 419 (38.1) 350 (37.8) 69 (39.9) 22 (32.8) 397 (38.5) Hemoptysis 10 (0.9) 6 (0.6) 4 (2.3) 2 (3.0) 8 (0.8) Shortness of breath 205 (18.7) 140 (15.1) 65 (37.6) 36 (53.7) 169 (16.4) Nausea or vomiting 55 (5.0) 43 (4.6) 12 (6.9) 3 (4.5) 52 (5.0) Diarrhea 42 (3.8) 32 (3.5) 10 (5.8) 4 (6.0) 38 (3.7) Myalgia or arthralgia 164 (14.9) 134 (14.5) 30 (17.3) 6 (9.0) 158 (15.3) Chills 126 (11.5) 100 (10.8) 26 (15.0) 8 (11.9) 118 (11.4) Signs of infection — no. (%) Throat congestion 19 (1.7) 17 (1.8) 2 (1.2) 0 19 (1.8) Tonsil swelling 23 (2.1) 17 (1.8) 6 (3.5) 1 (1.5) 22 (2.1) Enlargement of lymph nodes 2 (0.2) 1 (0.1) 1 (0.6) 1 (1.5) 1 (0.1) Rash 2 (0.2) 0 2 (1.2) 0 2 (0.2) Coexisting disorder — no. (%) Any 261 (23.7) 194 (21.0) 67 (38.7) 39 (58.2) 222 (21.5) Chronic obstructive pulmonary disease 12 (1.1) 6 (0.6) 6 (3.5) 7 (10.4) 5 (0.5) Diabetes 81 (7.4) 53 (5.7) 28 (16.2) 18 (26.9) 63 (6.1) Hypertension 165 (15.0) 124 (13.4) 41 (23.7) 24 (35.8) 141 (13.7) Coronary heart disease 27 (2.5) 17 (1.8) 10 (5.8) 6 (9.0) 21 (2.0) Cerebrovascular disease 15 (1.4) 11 (1.2) 4 (2.3) 4 (6.0) 11 (1.1) Hepatitis B infection¶ 23 (2.1) 22 (2.4) 1 (0.6) 1 (1.5) 22 (2.1) Cancer‖ 10 (0.9) 7 (0.8) 3 (1.7) 1 (1.5) 9 (0.9) Chronic renal disease 8 (0.7) 5 (0.5) 3 (1.7) 2 (3.0) 6 (0.6) Immunodeficiency 2 (0.2) 2 (0.2) 0 0 2 (0.2) * The denominators of patients who were included in the analysis are provided if they differed from the overall numbers in the group. Percentages may not total 100 because of rounding. Covid-19 denotes coronavirus disease 2019, and IQR interquartile range. † The primary composite end point was admission to an intensive care unit, the use of mechanical ventilation, or death. ‡ These patients were not residents of Wuhan. § Data regarding the incubation period were missing for 808 patients (73.5%). ¶The presence of hepatitis B infection was defined as a positive result on testing for hepatitis B surface antigen with or without elevated levels of alanine or aspartate aminotransferase. ‖ Included in this category is any type of cancer. The New England Journal of Medicine Downloaded from nejm.org at SOUTHERN MEDICAL UNIVERSITY on March 6, 2020. For personal use only. No other uses without permission. Copyright © 2020 Massachusetts Medical Society. All rights reserved