FULL CONTENTS Programmed Cell Death Is Regulated by Interactions with Peripheral Organization and Processing 540 Targets, Afferents, and Nonneuronal Cells 463 Central Pathways and Processing 542 The Role of Programmed Cell Death in Sensory Cortex 544 464 References 466 References 548 Suggested Readings 467 Suggested Readings 548 20. Synapse Elimination UAN C. TAPIA AND JEFF W. LICHTMAN 24. Chemical Senses: Taste and olfaction Overview 469 KRISTIN SCOTT The Purpose of Synapse Elimination 472 A Structural Analysis of Synapse Elimination at The Taste 549 Neuromuscular Junction 475 Olfaction 560 Role for Interaxonal Competition and Activity 478 Pheromone Detection 576 Is Synapse Elimination Strictly A Developmenta References 578 Summary 488 erences 25. Somatosensor 21. Dendritic Development STEWART HENDRY AND STEVEN HSIAO HOLLIS CLINE, ANIRVAN GHOSH, AND YUH-NUNG JAN Peripheral Mechanisms of Somatic Dynamics of Dendritic Arbor Development 491 Sensation 581 Genetic Control of Dendrite Development Nociception, Thermoreception, and Drosophila 492 Itch 589 Extracellular Regulation of Dendritic Development in Cns Components of Somatic Sensation 592 The Mammalian Brain 496 Thalamic Mechanisms of Somatic Effect of Experience on Dendritic Devel ensation 598 Mechanisms that Mediate Activity-Dependent Dendritic The Path From Nociception to Pain 598 Growth 507 The Trigeminal System 602 Convergence and Divergence 508 Cortical Representation of Touch 604 Conclusion 510 References 607 References 510 Suggested Readings 608 22. Early Experience and Sensitive Periods 26. Audition ERIC I KNUDSEN M. CHRISTIAN BROWN AND JOSEPH SANTOS-SACCHI Birdsong: Learned by Experience 517 External and middle ear 609 Sound Localization: Calibrated by Early Experience in the The Cochlea 610 Owl 520 The Auditory Nerve 618 Principles of Developmental Learning 529 Central Nervous System 624 References 635 Suggested Readings 636 SENSORY SYSTEMS 27. Vision R CLAY REID AND W. MARTIN USREY 23. Fundamentals of Sensory Systems STEWART H. HENDRY. STEVEN S HSIAO, AND Overview 637 M. CHRISTIAN BROWN The Eye and the Retina 639 The Retinogeniculocortical Pathway 649 Sensation and Perception 535 References 658 Receptors 537 Readings 659x FULL CONTENTS Programmed Cell Death Is Regulated by Interactions with Targets, Afferents, and Nonneuronal Cells 463 The Role of Programmed Cell Death in Neuropathology 464 References 466 Suggested Readings 467 20. Synapse Elimination JUAN C. TAPIA AND JEFF W. LICHTMAN Overview 469 The Purpose of Synapse Elimination 472 A Structural Analysis of Synapse Elimination at The Neuromuscular Junction 475 A Role for Interaxonal Competition and Activity 478 Is Synapse Elimination Strictly A Developmental Phenomenon? 488 Summary 488 References 489 21. Dendritic Development HOLLIS CLINE, ANIRVAN GHOSH, AND YUH-NUNG JAN Dynamics of Dendritic Arbor Development 491 Genetic Control of Dendrite Development in Drosophila 492 Extracellular Regulation of Dendritic Development in The Mammalian Brain 496 Effect of Experience on Dendritic Development 504 Mechanisms that Mediate Activity-Dependent Dendritic Growth 507 Convergence and Divergence 508 Conclusion 510 References 510 22. Early Experience and Sensitive Periods ERIC I. KNUDSEN Birdsong: Learned by Experience 517 Sound Localization: Calibrated by Early Experience in the Owl 520 Principles of Developmental Learning 529 References 532 IV SENSORY SYSTEMS 23. Fundamentals of Sensory Systems STEWART H. HENDRY, STEVEN S. HSIAO, AND M. CHRISTIAN BROWN Sensation and Perception 535 Receptors 537 Peripheral Organization and Processing 540 Central Pathways and Processing 542 Sensory Cortex 544 Summary 548 References 548 Suggested Readings 548 24. Chemical Senses: Taste and Olfaction KRISTIN SCOTT Taste 549 Olfaction 560 Pheromone Detection 576 References 578 Suggested Readings 579 25. Somatosensory System STEWART HENDRY AND STEVEN HSIAO Peripheral Mechanisms of Somatic Sensation 581 Nociception, Thermoreception, and Itch 589 Cns Components of Somatic Sensation 592 Thalamic Mechanisms of Somatic Sensation 598 The Path From Nociception to Pain 598 The Trigeminal System 602 Cortical Representation of Touch 604 References 607 Suggested Readings 608 26. Audition M. CHRISTIAN BROWN AND JOSEPH SANTOS-SACCHI External and Middle Ear 609 The Cochlea 610 The Auditory Nerve 618 Central Nervous System 624 References 635 Suggested Readings 636 27. Vision R. CLAY REID AND W. MARTIN USREY Overview 637 The Eye and the Retina 639 The Retinogeniculocortical Pathway 649 References 658 Suggested Readings 659