Synthesis of Amines Reductive Amination of Aldehydes and Ketones Amines can be synthesized in a single step from aldehydes or ketones with ammonia in the presence of a reducing agent Synthesis called a reductive amination CH3 CH3 NH3 H20 H2/Ni H NH2 (or NaBH4) Phenylpropan-2-one Amphetamine Cngage Leamng All Righs Resarvd Reductive Amination of Aldehydes and Ketones ▪ Amines can be synthesized in a single step from aldehydes or ketones with ammonia in the presence of a reducing agent ▪ Synthesis called a reductive amination Synthesis of Amines