S. Aureus Pathogenesis Combined effect of extracellular factors and toxins together with invasive properties of the strain More dangerous strains of s Aureus causes focal abscess that can spread via lymphatics or blood Can result in meningitis, endocarditis and sepsis Can also causes disease through toxins: SSss and TssS. Aureus Pathogenesis • Combined effect of extracellular factors and toxins together with invasive properties of the strain • More dangerous strains of S.Aureus causes focal abscess that can spread via lymphatics or blood. • Can result in meningitis, endocarditis, and sepsis • Can also causes disease through toxins: SSSS and TSS