S Pyogenes Virulence Factors 1. Structural Components carbohydrate-based bacterial capsule composed of hyaluronic acid M protein inhibit opsonization poteichoic acid and protein F(Sfbl)allow attachment to various host cells 2. Toxins and Superantigens Streptolysin O is a exotoxin of beta hemolytic Group property Streptolysin S is a cardiotoxic exotoxin that is another beta hemolytic component EXotoxin A, B, and c are superantigens cause sTss and scarlet fever 3. EnzymesS. Pyogenes Virulence Factors 1. Structural Components – carbohydrate-based bacterial capsule composed of hyaluronic acid – M protein inhibit opsonization – lipoteichoic acid and protein F (SfbI) allow attachment to various host cells 2. Toxins and Superantigens – Streptolysin O is a exotoxin of beta hemolytic Group property – Streptolysin S is a cardiotoxic exotoxin that is another beta￾hemolytic component – Exotoxin A, B, and C are superantigens cause STSS and scarlet fever 3. Enzymes