3. Infection process(development, and outcomes) 4. Nosocomial infections and their prevention Lecture Five Immune Responses to bacterial Infections 1. Immunity and immune responses against bacterial infection 2. Mechanisms of innate immunity(barriers, phagocytes, complement system etc 3. Mechanisms of specific host defense(humoral immunity, cell-mediated immunity heir activities on exocellular or intracellular bacterial infection Lecture Six Antimicrobial Chemotherapy, drug resistance and its prevention, Laboratory Diagnosis, Control of bacterial diseases 1. Antimicrobial Chemotherapies and their targets 2. Drug resistance, drug-bacteria relationship, clinical implications, and prevention 3. Diagnostic medical microbiology(collect samples, culture, iden diagnosis, immunologic or molecular diagnostic tests 4. Prevention of bacterial infection( active immunization, vaccines, and passive immunization) Lecture Seven Cocci 1. Staphylococci(pyogenic cocci and coagulase-negative staphylococcus) () Morphology, culture, and biological characteristics of Staphylococcus aureus (2)The virulence factors of Staphylococcus aureus and their effects includ ing SPa coagulase, hemolysin, and enterotoxin) ()The diagnostic laboratory tests for Staphy lococcus aureus and the principles of controlling Staphylococcus infections 2. Streptococcus(classification (1)Morphology, culture, and biological characteristics of Streptococcus (2) The virulence factors of group A streptococcus, the pyogenic and non- pyogenic infections caused by group A streptococcus, diseases caused by group B, D streptococcus and enterococcus (streptoly n, pyrogenic exotoxin, Invasive (3) The diagnostic laboratory tests for streptococcus and pneumococcus antistreptolysin O test(ASO test) (1)Classification of Neisseria(Neisseria meningitides and Neisseria gonorrhoeae) (2)The biolog ical characteristics and pathogenicity of-and immune response to Neisseria meningitides reatment of the d iseases caused by Neisseria meningitides (4) Neisseria gonorrhoeae and infection Lecture Eight Enterobacteriaceae: General introduction, Escherichia coli Shigella 1. General characterization and classification of Enterobacteriaceae 2. Escherichia coli5 / 11 3．Infection process (development, and outcomes) 4．Nosocomial infections and their prevention Lecture Five Immune Responses to bacterial Infections 1. Immunity and immune responses against bacterial infection 2. Mechanisms of innate immunity (barriers, phagocytes, complement system etc.) 3. Mechanisms of specific host defense (humoral immunity, cell-mediated immunity, their activities on exocellular or intracellular bacterial infection. Lecture Six Antimicrobial Chemotherapy, drug resistance and its prevention, Laboratory Diagnosis, Control of bacterial diseases 1. Antimicrobial Chemotherapies and their targets 2. Drug resistance, drug-bacteria relationship, clinical implications, and prevention 3. Diagnostic medical microbiology (collect samples, culture, identification, rapid diagnosis, immunologic or molecular diagnostic tests ) 4. Prevention of bacterial infection ( active immunization, vaccines, and passive immunization) Lecture Seven Cocci 1. Staphylococci (pyogenic cocci and coagulase-negative staphylococcus) (1) Morphology, culture, and biological characteristics of Staphylococcus aureus (2) The virulence factors of Staphylococcus aureus and their effects ( including SPA, coagulase, hemolysin, and enterotoxin) (3) The diagnostic laboratory tests for Staphylococcus aureus and the principles of controlling Staphylococcus infections 2. Streptococcus (classification) (1) Morphology, culture, and biological characteristics of Streptococcus (2) The virulence factors of group A streptococcus, the pyogenic and non- pyogenic infections caused by group A streptococcus, diseases caused by group B, D streptococcus and enterococcus (streptolysin, pyrogenic exotoxin, invasive enzymes) (3) The diagnostic laboratory tests for streptococcus and pneumococcus; antistreptolysin O test (ASO test) 3. Neisseria (1) Classification of Neisseria (Neisseria meningitides and Neisseria gonorrhoeae) (2) The biological characteristics and pathogenicity of - and immune response to - Neisseria meningitides (3) Principles of diagnostic laboratory tests, and principles of prevention and treatment of the diseases caused by Neisseria meningitides (4) Neisseria gonorrhoeae and infection Lecture Eight Enterobacteriaceae: General introduction, Escherichia coli & Shigella 1. General characterization and classification of Enterobacteriaceae 2. Escherichia coli