Low WSS(扩y依力Hypothesis(Caro,1971)IVERSITY High WSS Hypothesis(Fry,1972) Oscillatory WSS Hypothesis(Ku,1985) Any Correlations? Hemodynamic← Cardiovascular diseases factors Modeling&computation [Anor et al.,Systems Biology and Medicine 2010] [Liang et al.,Computers in Biology and Medicine 2007] Arterial system [Vignon-Clementel et al.,Computational Methods 9 on Applied Mechanics and Engineering 2006]Arterial system [Liang et al., Computers in Biology and Medicine 2007] [Vignon-Clementel et al., Computational Methods on Applied Mechanics and Engineering 2006] [Anor et al., Systems Biology and Medicine 2010] 9 Hemodynamic factors Cardiovascular diseases Any Correlations? Modeling& computation Low WSS (ずり応力) Hypothesis (Caro, 1971) High WSS Hypothesis (Fry, 1972) Oscillatory WSS Hypothesis (Ku, 1985)