Inhibition can be a source of insight into the mechanism of enzyme action:研究角度：探索酶催化机制 -Specific inhibitors can often be used to identify residues critical for catalysis. -Transition state analogs are especially potent inhibitors. H2N HN Figure 8.16 Enzyme inhibitors.The substrate dihydrofolate and its 二氢叶酸' Dihydrofolate structural analog methotrexate.Regions with structural differences are shown in red. 甲氨蝶呤 (一种抗肿瘤药)MothotrexatoFigure 8.16 Enzyme inhibitors. The substrate dihydrofolate and its structural analog methotrexate. Regions with structural differences are shown in red. Inhibition can be a source of insight into the mechanism of enzyme action: 研究角度：探索酶催化机制 -Specific inhibitors can often be used to identify residues critical for catalysis. -Transition state analogs are especially potent inhibitors. 甲氨蝶呤 （一种抗肿瘤药) 二氢叶酸