Enzyme inhibition types酶抑制剂类型 Irreversible inhibition.不可逆抑制：An irreversible inhibitor dissociates very slowly from its target enzyme because it has become tightly bound to the enzyme, either covalently or noncovalently. E+I EI Some irreversible inhibitors are important drugs. Penicillin acts by covalently modifying the enzyme transpeptidase(转肽酶)，thereby preventing the synthesis of bacterial cell walls and thus killing the bacteria(p.232) Aspirin acts by covalently modifying the cyclooxygenase(环氧化酶)，reducing the synthesis of signaling molecules involved in inflamation (p.139).Irreversible inhibition不可逆抑制: An irreversible inhibitor dissociates very slowly from its target enzyme because it has become tightly bound to the enzyme, either covalently or noncovalently. E + I EI Some irreversible inhibitors are important drugs. - Penicillin acts by covalently modifying the enzyme transpeptidase （转肽酶）, thereby preventing the synthesis of bacterial cell walls and thus killing the bacteria (p. 232). - Aspirin acts by covalently modifying the cyclooxygenase（环氧化酶）, reducing the synthesis of signaling molecules involved in inflamation (p. 139). Enzyme inhibition types 酶抑制剂类型