Localization of metabolic functions within the mitochondrion Outer membrane Inner membrane. Phospholipid synthesis Electron transport fatty acid desaturation Oxidative phosphorylation Fatty acid elongation Metabolite transport Matrix Intermembrane space Pyruvate oxidation Nucleotide phosphorylation TCA cvcle B oxidation of fats DNA replication, RNA transcription Protein translationLocalization of metabolic functions within the mitochondrion Outer membrane: Phospholipid synthesis fatty acid desaturation Fatty acid elongation Inner membrane: Electron transport Oxidative phosphorylation Metabolite transport Intermembrane space Nucleotide phosphorylation Matrix Pyruvate oxidation TCA cycle ß oxidation of fats DNA replication, RNA transcription, Protein translation