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Anhui Medical and Pharmaceutical Journal 2017 Oct, 21(10) ·1759 105(1):3596 173 CAVUS 1, DUMAN RS. Influence of estradiol, stress and 5-HT2A 57] MOGHADDAM B, ADAMS B, VERMA A, et al. Activation of glu monist treatment on brain -derived neurotrophic factor expression in amatergic neurotransmission by ketamine: a novel step in the path- female rats [. Biol Psychiatry, 2003, 54(1):5949. way from NMDA receptor blockade to dopaminergic and cognitive 174] WEI J, YUEN EY, LIU W,et al. Estrogen protects against the det- cortex rimental effects of repeated stress on glutamatergic transmission 1997,17(8):29212927 and cognition [. Mol Psychiatry, 2014, 19(5): 588-598 [58] ZHANG TY, LABONTEE B, WEN XL, et al. Epigenetic mecha 15] SPENCER JL, WATERS EM, ROMEO RD, et al. 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Skeletal muscle PGC-1 1 modulates kynurenine metabolism and mediates resilience to stress-induced depression[J]. Cell,2014,159( 1) : 33-45. [88] VOSS MW,VIVAR C,KRAMER AF,et al. Bridging animal and human models of exercise-induced brain plasticity[J]. Trends Cogn Sci,2013,17( 10) : 525-544. [89] LU XY,KIM CS,FRAZER A,et al. Leptin: a potential novel antide￾pressant[J]. Proc Natl Acad Sci USA,2006,103( 5) : 1593-1598. [90] PALAZIDOU E. The neurobiology of depression[J]. Br Med Bull, 2012,101: 127-145. ( 收稿日期: 2016-10-23,修回日期: 2016-11-05) 安 徽 医 药 Anhui Medical and Pharmaceutical Journal 2017 Oct,21( 10) ·1759·
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