developing and trying to merge with the westem medicine, so the medicine will get better each year. So I hope someday, the diabetes can treat without the chemical medicine, and the people are difficult to get any kinds of the disease References Shimomura l hammer re richardson ja ikemoto s. bahmakoy y goldstein jl and brown MS: Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Drc Kim HJ, Takahashi M and Ezakio(1999): Fish oil feeding decreases mature sterol regulatory element-binding protein 1(SREBP-1)by down regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAS Shimono H(2001): Sterol regulatory element binding proteins(SREBPS): transcrip regulators of lipid syn gene Ansderson JW, Johnstone BM and Cook-Newell ME(1995): MetaAnalysis of the effects of soy protein intake on serum lipids Lovati MR, Manzoni C, Gianazza E, Arnoldi A, Kurowska E, Carroll KK and Sirtori CR(2000) Soy protein peptides regulate cholesterol homeostasia in Hep G2 cells Nutr Lucas EA, Khalil DA, Daggy BP and Arjmandi BH (2001): Ethanol-extracted soy protein isolate does not modulate serum cholesterol in golden Syrian hamsters; a model of postmenopausal hypercholesterolemia Lacigne C, Tremblay F, Asselin G, Jacques H and Marette A(2001): Prevention of skeletal muscle insulin resistance by dietary cos protein in high fat-fed ratsdeveloping and trying to merge with the western medicine, so the medicine will get better each year. So I hope someday, the diabetes can treat without the chemical medicine, and the people are difficult to get any kinds of the disease. References . Shimomura I, Hammer RE, Richardson JA, Ikemoto S, Bahmakov Y, Goldstein JL and Brown MS: Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Drc. Kim HJ,Takahashi M and Ezaki O (1999): Fish oil feeding decreases mature sterol regulatory element-binding protein 1(SREBP-1) by down regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs. Shimono H(2001): Sterol regulatory element binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Ansderson JW, Johnstone BM and Cook-Newell ME (1995) : Meta0analysis of the effects of soy protein intake on serum lipids. Lovati MR, Manzoni C, Gianazza E, Arnoldi A, Kurowska E, Carroll KK and Sirtori CR (2000): Soy protein peptides regulate cholesterol homeostasia in Hep G2 cellsJ Nutr Lucas EA, Khalil DA, Daggy BP and Arjmandi BH (2001): Ethanol-extracted soy protein isolate does not modulate serum cholesterol in golden Syrian hamsters; a model of postmenopausal hypercholesterolemia. Lacigne C, Tremblay F, Asselin G, Jacques H and Marette A (2001): Prevention of skeletal muscle insulin resistance by dietary cos protein in high fat-fed rats