河北医科大学药学院 天然杀虫剂一Pyrethrin 印楝一“可解决全球问题之树 The new way to keep insects away 除多葡内丽 除支大师 油菜素内酯Brassinolide 他感物质Allelochemics #罗夹Gmve时零17匀用227起尚兼花条能痕样到10m的南常性蜂毒物围 有麻聊参是风肉、抑制汗赚分法华作用，能核载大多数动 新的食。 Anatoxin-a,A Very Fast Death Factor Cytisine:A smoking cessation drug molecule Anatexia is a sever 天然药物化学教研室史清文教授 河北医科大学药学院 天然药物化学教研室史清文教授 7 O O O 天然杀虫剂—Pyrethrin Pyrethrin was isolated from the flower of Pyrethrum cinerariifolium Trev，Chrysanthemun Cinerariaefolium. Which was used as an insecticide. 除虫菊内酯 印楝— “可解决全球问题之树” The new way to keep insects away Azadirachta Indica A. Juss Prof. Steve Ley “除虫大师” MeO2C O O O O OH O H AcO O O H OH CO2Me OH Azadiractin 油菜素内酯 Brassinolide O OH H HO HO OH H H 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 O HO 24 25 26 27 28 H 油菜素内酯是从油菜花粉中分得的植物生长促进剂，可使多种 作物增产。 1. 促进细胞伸长和分裂 2. 促进光合作用 3. 提高抗逆性 格罗夫(Grove)等(1979)用227kg油菜花粉提取得到10mg的高活性结晶物BR1. 被国际上誉为第六激素，属新型广谱植物生长调节剂 芸苔素内酯 茄科植物曼陀罗的花在我国古代用来制造“蒙汗 药”，因为其中含有莨菪碱、东莨菪碱及少量阿托品等， 有麻醉松弛肌肉、抑制汗腺分泌等作用，能抵抗大多数动 物的啃食。 阿托品 东莨菪碱 O OH N CH3 O OH O N CH3 O O Atropine Scopolamine 他感物质Allelochemics 281 Anatoxin-a, A Very Fast Death Factor Anatoxin-a was first discovered by P.R. Gorham in the early 1960s, after several herds of cattle died as a result of drinking water from Saskatchewan Lake in Ontario, Canada, which contained toxic algal blooms. It was isolated in 1972 by J.P. Devlin from the cyanobacteria Anabaena flos-aquae. cyanobacteria Anabaena flos￾aquae 水华鱼腥藻 Anatoxin is a severe neurotoxin 282 Golden rain tree, Laburnum anagyroides Cytisine 野靛碱 Cytisine: A smoking cessation drug molecule Cytisine is a partial agonist of nicotinic acetylcholine receptors (nAChRs)