Similarity of regulation between eukaryotes and prokaryote 1.Principles are the same: • signals (信号), • activators and repressors (激活蛋白和阻 遏蛋白) • recruitment and allostery, cooperative binding (招募，异构和协同结合) 2. The gene expression steps subjected to regulation are similar, and the initiation of transcription is the most pervasively regulated step
The purpose of a receiver is to select a desired group of frequencies from one transmitter, get rid of all unwanted signals and noise, and then demodulate the signal to obtain the modulating infomation. The better the receiver does its job, the closer the demodulated sigmal will resemble the original signal from the transmitter. Regardless of the type of demodula
Sound knowledge of linear algebra and calculus Signals and systems (ECE 351 and ECE 352 or equivalent courses) Basic Matlab programming skillsRequirements
8.1 Introduction 8.2 Chaperones may be required for protein folding 8.3 Post-translational membrane insertion depends on leader sequences 8.4 A hierarchy of sequences determines location within organelles 8.5 Signal sequences initiate translocation 8.6 How do proteins enter and leave membranes? 8.7 Anchor signals are needed for membrane residence 8.8 Bacteria use both co-translational and post-translational translocation 8.9 Pores are used for nuclear ingress and egress 8.10 Protein degradation by proteasomes
