Introduction All babies develop elevated serum bilirubin (SBR) levels, to a greater or lesser degree, in the first week of life. This is due to: increased production(accelerated RBC breakdown); decreased removal (liver enzyme insufficiency) Increased reabsorption(enterohepatic circulation)

1. To master growth patterns of common used growth parameters. 2. To understand how to assess growth and development. 3. To know the important regularities of growth and development

Bacteremia and Septicemia Bacteremia: a more benign infection with entrance of bacteria into the bloodstream, but in limited quantities. Septicemia: an overwhelming infection with more organism or more virulent organisms that is likely to lead to shock or other complications

一、病因 控制血红蛋白肽链合成基因的遗传缺陷或突变,致使肽链合成障碍(合成速率变慢,合成量减少)

Etiology and Epidemiology of ICH >Trauma (epidural, subdural, or subarachnoid) fetal head is too large in proportion to the size of the pelvic outlet prolonged labor/breech or precipitate deliveries

Introduction Growth and growth disorders Adrenal disorders and sexual development abnormalities Thyroid disorders Disorders of calcium and phosphorus metabolism Diabetes mellitus and hypoglycemia Other disorders: obesity, autoimune

Introduction GHD is a disorder involves the pituitary gland Pituitary gland does not produce enough GH Growth velocity is slower than normal GHD can occur at any age

Introduction Growth and growth disorders Adrenal disorders and sexual development abnormalities Thvroid disorders Disorders of calcium and phosphorus metabolism Diabetes mellitus and hypoglycemia Other disorders: obesity, autoimune endocrinopathies, tumor, inborn metabolic

Introduction GHD is a disorder involves the pituitary gland Pituitary gland does not produce enough gh Growth velocity is slower than normal GHD can occur at any age

One pairofchromosome 21 was seen in peripheral lymphocytes of normal person 15