Chapter 6 Ionic Reactions--- Nucleophilic substitution and elimination reactions of alkylhalides (卤代烃的亲核取代反 Because halogen atoms are more electronegative 应和消除反应） than carbon, the carbon-halogen bond of alkyl halides is polarized; the carbon atom bears a partial positive charge, the halogen atom a partial negative charge

The important of acid-base reaction: 1. is a simple, fundamental reaction. 2. enable you to see the mechanism of the reaction 3. illustrate the process of bond breaking and bond making 4. examine important ideas about the relationship between the structure of molecules and their reactivity

18.1 Introduction The carboxyl group, -COOH, -CO2H, is one of the most widely occurring functional groups in chemistry and biochemistry. Not only are carboxylic acids themselves important, but the carboxyl group is the parent group of a large family of related compounds

Carbon’s ability to form strong covalent bonds to other carbon atoms is the single property of the carbon atom that — more than any other—accounts for the existence of a field of study called organic chemistry. Carbon’s ability to form as many as four strong bonds to other carbon atoms, and to form strong bonds to hydrogen, oxygen, sulfur, and nitrogen atoms as well

An acid is a substance that can donate (or lose) a proton, A base is a substance that can accept (or remove) a proton

Energy and the Relative Stability Kinetic energy is the energy an object has because of its motion. Potential energy is stored energy. It exists only when an attractive or repulsive force exists between objects

Cycloalkanes with only one ring are named by attaching the prefix cyclo- to the names of the alkanes possessing the same number of carbon atoms

The different arrangements of atoms caused by rotation about a single bond are called conformations (构象)of the molecule, and a specific conformation is called a conformer (构象异构体, conformation isomer). An analysis of the energy changes that a molecule undergoes as groups rotate about single bonds is called a conformational analysis (构象分析)

Isomers are different compounds that have the same molecular formula. Constitutional isomers are isomers that differ because their atoms are connected in a different order. Stereoisomers differ only in arrangement of their atoms in space.Stereoisomers are not constitutional isomers. Enantiomers are stereoisomers whose molecules are nonsuperposable mirror images of each other. Diastereomer are stereoisomers whose molecules are not mirror images of each other

Before 1951 only relative configurations of chiral molecules were known. Configurations of chiral molecules were related to each other through reactions of known stereochemistry. The standard compound was glyceraldehyde