Biodegradable Solid Polymers Spring 2003 Issued Day 1 Day 3 1. The chemical structure of a new degradable polymer, poly (ethylene glycol)-b-polylysine-b- poly (D, L-lactide)

1. Re-derive the equation for equilibrium swelling of a polyelectrolyte gel where the polymer chains contain a basic ionizable group that becomes positively charged with decreasing pH

1. Re-derive the equation for equilibrium swelling of a polyelectrolyte gel where the polymer chains contain a basic ionizable group that becomes positively charged with decreasing pH

engineering intracellular delivery Drug targeting Today biosensor device classes Detection methods Overview of biosensor technology Classes of biosensor devices External analysis/detection

Lecture 5: Controlled Release Devices Last time: Using enzyme substrate and cytokine peptides to engineer biological recognition of synthetic polymers Today: principles of controlled release devices based on degradable polymers Synthesis of controlled release devices Theory of polymer-based controlled release

Molecular Principles of Biomaterials Spring 2003 Lecture 2: Molecular Design and Synthesis of Biomaterials I: Biodegradable Materials Chemistry of Biodegradable Materials Hydrolytically degraded biomaterials Common hydrolytically unstable linkages Ester

Experimental Foods Carbohydrates Starch and Sugars Alternative Sweeteners

Live difficult diagnosis clinical picture, skin biopsy, corneal impression(antibodies only appear very late) Dead- brain sent to Onderstepoort Negri bodies in cytoplasm of brain cells; immunofluorescence virus isolation

Human cytomegalovirus Epstein-Barr- virus Herpes simplex virus Yellow fever virus Rubella

Properties of herpesviruses Enveloped double stranded DNA viruses. Genome consisits of long and short fragments which may be orientated in either direction, giving a total of 4 isomers