Review of DNA Seq. Comparison/Alignment Target frequencies and mismatch penalties Eukaryotic gene structure Comparative genomics applications Pipmaker(2 species comparison) Phylogenetic Shadowing(many species) Intro to DNA sequence motifs

The Language of genomics CDNAS, ESTS. BACS Alus. etc Dideoxy Method Shotgun Sequencing The 'shotgun coverage equation(Poisson) Flavors of blast BLASTIPNXJ, TBLASTINXI Statistics of High Scoring Segments

Outline FASTA, Blast searching, Smith-Waterman Psi-Blast Review of Genomic DNA structure Substitution patterns and mutation rates Synonymous and non-Synonymous substitutions Jukes-Cantor Model Kimura's Two-Parameter Model

Categories of Respiratory Viruses Orthomyxoviridae: Influenza virus Paramyxoviridae: Parainfluenza virus, Mumps virus; Measles, Respiratory syneytical virus Togaviridae: Rubella virus Coronaviridae: corona irus, sars virus Adenoviridae: human Adenovirus picornaviridae: Rhino virus;

Viral gastroenteritis It is thought that viruses are responsible for up to 3/4 of all infective diarrhoeas Viral gastroenteritis is the second most common viral illness after upper respiratory tract infection

Genera of picornaviruses Enterovirus Polio Diseases of the human (and other alimentary tract Coxsackie a and B (e.g. polio virus

Chapter 2 Application Layer Computer Networking: A Top Down Approach The PowerPoint Slides are based on Featuring the Internet, 2nd edition. the material provided by Jim Kurose, Keith Ross .F Kurose and K.W. Ross. Addison-Wesley, July

Chapter 3 Transport Layer Computer Networking The Powerpoint slides are based on the A Top Down Approach material provided by Featuring the Internet J F Kurose and K.W. Ross 2nd edition

铝轮冒口切断机 Overflow cutting machines for aluminium whee 离心压力机 Presses, eccentric 六角立式铣床 Milling machines, turret vertical 六角车床 Lathes, turret 螺栓,螺帽及螺丝Bots, screws&nuts

Chapter 4 Network Layer Computer Networking: A Top Down Approach Featuring the Internet The PowerPoint Slides are based on the material 2nd edition. provided by Jim Kurose, Keith Ross