第一节 概述 第二节 甜味及甜味物质 第三节 苦味及苦味物质 第四节 咸味物质 第五节 酸味及酸味物质 第六节 辣味及辣味物质 第七节 鲜味及鲜味物质 第八节 涩味及涩味物质

Major Steps in Discovery Stage Target generation and selection Development Method set-up Method validation Technique assesment Assay development and validation Automation Optimization Compound Library High throughput screens Combinatorial chemistry Library chemistry Natural products Lead confirmation and chemistry Preliminary PK investigation SAR In vivo functional tests

1 Introduction to medicinal chemistry 2 General priciples of drug action 3 Physico chemical properties of organic medicinal agents 4 Chemistry of prodrugs 5 Drug metabolism 6 General anesthetics 7 Sedative-hypnotic drugs 8 Psychoactive drugs 9 Antiepileptic agents 10 Cholinergic and anticholinergic drugs 11 Adrenergic drugs 12 Adrenoreceptor blocking drugs 13 Skeletal muscle relaxants 14 Antihistamines 15 Narcotic analgesics 16 Narcotic antagonists 17 Antitussives 18 Non-steroidal antiinflammatory drugs 19 Local anesthetics 20 Diuretics 21 Hypoglycemic agents 22 Thyroid and antithyroid drugs

9.1 The ionic radii ratio and the coordination polyhedra of ions 9.2 The crystal structures of Some typical ionic compounds 9.3 Lattice energy 9.4 Ionic radii 9.5 The Pauling rule of ionic crystal structure 9.6 Structural chemistry of silicates 9.7 Crystals of Functional Materials

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McGraw-Hill Higher Education A Division of The McGraup-Hill Companies MODERN ANALYTICAL CHEMISTRY Copyright e 2000 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 976, no part of this publicatio

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CHEMICAL ANALYSIS A SERIES OF MONOGRAPHS ON ANALYTICAL CHEMISTRY AND ITS APPLICATIONS Editor . D. WINEFORDNER Ⅴ OLUME162 A complete list of the titles in this series appears at the end of this volume

Chapter 8 Soil colloidal chemistry and soil surface reaction 阳离子交换机制