安庆医药高等专科学校：《病原生物与免疫学》课程PPT教学课件（寄生虫学）实验五寄生虫实验

▪ 酶是活细胞产生的一类具有催化功能的蛋 白质，亦称为生物催化剂Biocatalysts 。 ▪ 绝大多数的酶都是蛋白质(Enzyme和 Ribozyme)。 ▪ 酶催化的生物化学反应，称为酶促反应 Enzymatic reaction。 ▪ 在酶的催化下发生化学变化的物质，称为 底物substrate

Overall Strategies Defense against complement Subversion of phagocytosis Subversion of immune responses

Types of chemotaxins – C5a attracts neutrophils and monocytes – Made by bacteria Peptide clipped off N-terminus (beginning with N￾formylmethionine) during peptide maturation after protein synthesis

Constitutive Defenses Barriers to entry – See Schaechter text, Table 6.1 Mucous membranes—covered by protective layer of mucus – Mechanical and chemical barrier that allows proper functioning

Operon fusion: transcriptional – Promoter from foreign gene – Translational sequence from reporter gene

Choosing an Animal Model Pathogen may not affect animal at all -OR￾may give different symptoms Given disease may have a number of animal models, none of which fully satisfies characteristics of disease

《微生物学》课程教学课件（Food Microbiology）Stain Protocols – BIOL 2420

《微生物学》课程教学课件（Food Microbiology）SELECTIVE AND DIFFERENTIAL MEDIA

General aspects – Remember definition: organisms frequently found on or within body of healthy individuals – Most are bacteria, but some are viruses, fungi, and protozoa