Outline 1. Irreversible injury 2. Regenerative and nonregenerative tissues 3. Antagonistic relation between contraction and regeneration 4. Present theory: Selective inhibition of contraction necessary but not sufficient for regeneration 5. Mechanism
Chapter 2. Cell-Matrix Interactions. [that determine biomaterials function in vitro and in vivo] A. How cells pull onto and deform the matrix to which they attach themselves. B. Cell-matrix interactions control the spontaneous closure of wounds in organs. C. What happens when regeneration is induced?
BIOMATERIALS-TISSUE INTERACTIONS: \Tools\ for Understanding the Molecular, Cellular, and Physiological, Bases of the Tissue Response to Implants M. Spector, Ph. D. and I. V. Yannas, Ph.D. BIOMATERIALS-TISSUE INTERACTIONS
Introduction. Chapter 1. Irreversible Healing of Extracellular Matrix. Chapter 2. Cell-Matrix Interactions. Chapter 3. Synthesis of Tissues and Organs. TEXT: I. V. Yannas. Tissue and Organ Regeneration in Adults. New York: Springer, 2001
TISSUE Tissue is a biological structure made up of cells of the same type. - Cells of the same phenotype(e., same genes expressed). An aggregation of morphologically similar cells and associated extracellular matrix acting together to perform one or more specific functions in the body. - There are four basic types of tissue: muscle, nerve, epithelia, and connective. An organ is a structure made up of or more tissues
Introduction The nervous tissue of animals responds to stimuli within and outside of the body. Incoming information is integrated and a response is made. The response is muscle contraction or secretion by a gland. The end hydra result is the maintenance of body functions or homeostasis
Price wars are bad, especially with high fixed costs They reduce current profits and erode customers' perception of product quality Price wars are not inevitable. For example the French and the Germans fight every fifty years but not every year
Price wars are bad, especially with high fixed costs. They reduce current profits and erode customers' perception of product quality. Price wars are not inevitable. For example, the French and the Germans fight every fifty years but not every year. But collusion is illegal
