华南师范大学：《医学分子生物学》课程教学课件（PPT讲稿）第五章 基因表达（转录）Gene Expression

General introduction Ion channels G-protein coupled receptors Second messengers Tyrosine kinase receptors From plasma membrane to the nucleus: Regulation of gene expression Cytokine signaling Cell cycle Apoptosis

RNA polymerase transcribes genes How is this process regulated? How is specificity achieved? Key players transcriptional activator proteins -bind to specific sites on DNA and turn on the expression of nearby genes. Two adhesive surfaces one binds DNA, the other interacts with, and recruits RNA polymerase

The nucleus is the biggest and most important organelle of the cell. The presence of the nucleus is the principal feature that distinguishes eukaryotic from prokaryotic cells Almost eukaryotic cells have the nucleus except mature red blood cells of mammals and sieve cells of high plants etc.. By housing the cell's genome, the nucleus serves both as the repository of genetic information and as the control

遗传:使微生物的性状保持其种属的稳定性; 变异:是微生物进化的基础; 基因(gene 基因型(genotype) 表现型( phenotype)

一、名词解释(每题2分) 1、近等基因系 2、结构域互换 3、e-dna 4、基因转换(gene comversion) 5、微排列(microarrang) 6、双向电泳

Genetic Engineering and Biotechnology Genetic engineering: Isolation manipulation and expression of genetic materials. Gene cloning: Isolation and purification of specific genes In vitro recombination=recombinant DNA

Wonder of the Genetic Engineering Expression of luciferase gene in a plant

Below is an electron micrograph of a single gene being transcribed. The DNA strand runs horizontally with RNa transcripts extending vertically outward Image removed due to copyright reasons a)Draw an arrow indicating the direction that the RNA polymerases are

1. What is gene therapy? Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins