Causation and Treatment Professor of Obstetrics, Northwestern University Medical School Jos. B. De Lee Published in Medicine (Detroit) 3: 643-660, 1897. The highest mortality that befalls the human race in one day occurs on the day of birth. It is said that the most important period of the life of a human being is the time spent in utero. The most trying ordeal a human being sustains is the ordeal of birth
Congenital Heart Diseases (CHD)先天性心脏病 General concept CHD occurs in approximately6-8‰ live births In China, alone 250000 children with CHD are b0r€aC1yaT 30% of cases may die within first year of life The etiology remains unsolved Secondary prevention is the strategy at this stage
Epidemiology of CHD Prevalence CHD occurs in 0.5-0.8% of live births; The incidence is higher among stillborns 死产(3-4%), abortuses流产(10-25%),and premature infants (about 2% excluding PDA); About 2-3 in 1,000 newborn infants will be symptomatic with heart disease in the first year of life