§1 蛋白质的营养作用 Nutrition of Protein §2 蛋白质的消化,吸收和腐败 Digestion, Absorbtion and Putrefaction of Protein 第三节 氨基酸的一般代谢 General Metabolism of Amino Acids 第四节 氨的代谢 Ammonia Metablism 第五节 个别氨基酸的代谢 metabolism of individual amino acid
1. Hemoglobin is a multisubunit allosteric protein that carries 02 in erythrocyte. 1.1 Hemoglobin is a well-studied and well-understood protein. 1.1.1 It was one of the first proteins to have its molecular mass accurately determined. 1.1.2 The first protein to be characterized by ultracentrifuge. 1.1.3 The first protein to be associated with a specific physiological function
1. General studies of the peptide bond 1.1 The peptide(O=C-N-H) bond was found to be shorter than the C-N bond in a simple amine and atoms attached are coplanar. 1.1.1 This was revealed by X-ray diffraction studies of amino acids and of simple dipeptides and tripeptides. 1.1.2 The peptide (amide) bond was found to be about 1.32 A (C-N single bond, 1.49; C= double bond, 1.27), thus having partial double bond feature (should be rigid and unable to rotate freely)