1. Discovery of cell and the evolution of cell theory. (~1850s) MJ. Schleiden (1804-1884): Beitrage zur Phytogehesis(植物发 生论), Arch Anat Physiol 1838, 137-176

Whole cell movement; cell shaping; Intracellular movements; membrane fluidity 1. Whole cell movement

—主要是非组蛋白对基因组的作用 细胞增殖、分化、凋亡的相互关系及其调控 细胞信号转导的研究

第一节 病毒的形态结构与化学组成 第三节 病毒的主要类群与繁殖方式

Announcements: Power Point Lecture Notes Available on BCMP200 Website For further reading Nucleic Acids: Structures, Properties, and Functions V.A. Bloomfield D. M. Crothers

Collaboration of Proteins at the Replication Fork Leading strand DNA polymerase lll Leadi ng strand template Lagging strand RNA primase template RNA primer

一、性别表现型的决定 二、生殖细胞(Germ Cells)的发育 三、受精

一、组织、器官、个体的生长 二、蜕皮(molting)和变形(metamorphosis) 三、个体衰老

Electron Microscopy of replicating DNA reveals replicating bubbles. How does one prove bidirectional fork movement?

Techniques to manipulate DNA Phenol/chloroform extraction Ethanol precipitation Concentration determination Gel Electrophoresis DNA hybridization Southern blotting Melting temperatures