MACINETIC RESONANCE ELSEVIER Progress in Nuclear Magnetic Resonance Spectroscopy 32(1998)287-387 The use of nmr methods for conformational studies of nucleic acids Sybren S. Wijmenga*, Bernd N M. van Buuren Umed University, Department of Medical Biochemistry and Biophysics, S 90187 Umed, Sweden

• 量子力学基础 • 密度算符 • 脉冲及其算符描述 • 核磁信号计算 • 多自旋体系的描述 • 相干 • 乘积算符

SPE'TROSCO)Y LSI in Nuclear Magnetic Resonance Spectroscopy 32(1998)193-275 Technical aspects of nmr spectroscopy with biological macromolecules and studies of hydration in solution erhard Wider Institut fur Molekularbiologie und Biophysik, Eidgenossische Technische Hochschule, Honggerberg, CH-8093 Zurich, Switzerland

NMR screening in drug discovery Jonathan M Moore NMR methods in drug discovery have traditionally been used drugs. Many pharmaceutical industry research groups have to obtain structural information for drug targets or embarked on drug discovery programs using NMR screen-

NMR of drugs and ligands bound to receptors Anthony Watts NMR methods are now able to give detailed structural, dynamic of these still not identified or classed into families [4\]. and electronic information about drugs and ligands while

5 Heteronuclear Correlation Spectroscopy H.C-COSY We will generally discuss heteronuclear correlation spectroscopy for x =C(in natura abundance!), since this is by far the most widely used application. However, all this can also be applied to other heteronuclear spins, like 3P, 5N, 1%F,etc In the heteronuclear case, there are some important differences that allow to

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY ELSEVIER Progress in Nuclear Magnetic Resonance Spectroscopy 38 (2001) 325-360 www.elsevier.nl/locate/pnmrs NMR quantum computation J.A. Jonesa,b,* \Oxford Centre for Molecular Sciences. New Chemistry Laboratory South Parks Road, Oxford OXI 3QT. UK

Dictionary A chemical-shift reference is used to define the (CH3)4SI positions of the resonances in the spectrum in terms of parts-per-million, or ppm, of frequency It is a material which is often directly added to the

2 Basis Principles of FT NMR C Gerd Gemmecker 1999 Nuclei in magnetic fields Atomic nuclei are composed of nucleons, i.e., protons and neutrons. Each of these particles shows a property named\spin\(behaving like an angular momentum) that adds up to the total spin of the

§12-1 红外光谱 §12-1 核磁共振波谱 §12-1 有机质谱 §12-1 波谱的综合利用