Overview Clinical syndrome Slowing down of metabolism Slowing of growth and mental retardation in infants and children Generalized slowing down of organism Deposition of glycosaminoglycans in skin and muscle Reversible with therapy

Cirrhosis---definition chronic, progressed, diffuse hepatocellular injury fibrosis nodular regeneration

Key Words Respiratory failure Acute respiratory distress syndrome(ARDS) dyspnea Hypoxemia hypercapnia Respiratory Support

Cardiovascular disease Cerebrovascular diseases Lower respiratory infections Diarrhea Perinatal disease COPD Tuberculosis Morbilli

Chapter three Chronic Obstructive Pulmonary Diseases (COPD) Chronic Bronchitis Obstructive Pulmonary Emphysema

Concept of leukemia Definition It is the results of the tumor proliferation of heamotopoietic stem cells.（造血干细胞） Leukemia is a malignant blood disorder. (not solid tumor)

（一）熟悉骨质疏松症的概念、分型及发病机制 （二）掌握骨质疏松症的诊断、防治及药物治疗 （三）了解骨质疏松症的流行病学与病因学

Factors cause diseases： chemicals physical biological psychological chemicals：occupational, non-occupational. physical：occupational, non-occupational

Bone marrow hematopoiesis failure led by chemicals, radiation, biological factors and unknown etiology. The common clinical presentation is mild to severe pancytopenia

Chronic Renal Insufficiency Pathogen and pathogenesis Manifestation Laboratory examination Diagnosis and differential diagnosis Treatment