I. Symbioses between Microorganisms II. Plants as Microbial Habitats 2. The Legume–Root Nodule Symbiosis 3. Agrobacterium and Crown Gall Disease 4. Mycorrhizae III. Animals as Microbial Habitats 5. The Mammalian Gut 6. The Rumen and Ruminant Animals 7. The Human Microbiome 8. Termites

12.1 Early Microbial Life on Earth 12.1.1 Conditions on Early Earth: hot and Anoxic 12.1.2 Evidence for Life on early Earth: Stromatolites 叠层石 12.2 Origin of Cellular life 12.3 Primitive Life: Early Metabolism 12.4 Eukaryotes and Organelles: Endosymbiosis 内共生

1、酶促反应动力学的特点 2、均相酶促反应动力学 3、固定化酶促反应动力学 4、酶的失活动力学

18.10 Fungi 真菌 18.10.1 Fungal Physiology, Structure, and Symbioses 18.10.2 Fungal Reproduction and Phylogeny Chen Feng, Shanghai Jiao Tong University 18.10.3 Filamentous Fungi: Molds 18.10.4 Macroscopic Fungi: Mushrooms大型真菌:蘑菇 18.10.5 Unicellular 18.11 Algae 藻类 Fungi: Yeasts

I. Bacterial Cell Division 5.1 Cell Growth and Binary Fission 5.2 Fts proteins and the cell division plane 5.3 Peptidoglycan synthesis and cell division 肽聚糖合成与细胞分裂 5.4 Growth terminology and the concept of exponential growth 5.5 The mathematics of exponential growth 5.6 The Growth Cycle 生长周期

5.10 Effect of Temperature on Growth 5.11 Microbial growth at cold temperatures 5.12 Microbial growth at high temperatures 5.14 Osmotic Effects on Microbial Growth 渗透压影响 5.15 Oxygen and microbial growth Aerobes好氧菌 • Strict Aerobes专性好氧菌 • Microaerophiles微好氧菌 • Facultative aerobes兼性好氧菌 Anaerobes厌氧菌 • Aerotolerant anaerobes耐氧的厌氧菌 • Obligate (strict) anaerobes专性厌氧菌 5.16 Toxic forms of oxygen

I. Physical Antimicrobial Control 6.1 Heat Sterilization 6.2 Radiation Sterilization 6.3 Filter Sterilization II. Chemical Antimicrobial Control Antiseptics防腐剂 Disinfectants消毒剂 Sterilants杀菌剂 6.4 Chemical Growth Control 6.4.1 Effect of antimicrobial agents on growth 6.4.2 Measuring antimcirobial activity 6.5 Chemical antimicrobial agents for external use

III. ANTIMICROBIAL AGENTS USED IN VIVO 体内使用的抗微生物制剂 Selective toxicity选择毒性 Can be used internally可体内使用 Chemotherapeutic agents化学治疗剂 6.6 Synthetic Antimicrobial Drugs 人工合成的抗微生物药物 6.7 Antibiotics: Naturally occurring antimicrobial drugs 抗生素 IV. ANTIMICROBIAL DRUG RESISTANCE AND DRUG DISCOVERY 抗药性与新药研制 6.8 Antimicrobial drug resistance

I. Overview of Regulation 8.1 Major modes of regulation II. Regulation of Enzyme Activity (Posttranslational level regulation) 8.2 Noncovalent enzyme inhibition 酶活的非共价抑制 8.3 Covalent Modification of Enzyme 酶的共价修饰 III. DNA-Binding Proteins and Regulation of Transcription by Negative and Positive Control (Transcriptional level regulation) 转录水平调控

III. DNA-Binding Proteins and Regulation of Transcription by Negative and Positive Control (Transcriptional level regulation) DNA结合蛋白与转录水平的调控 8.5 Negative control of transcription: Repression and Induction转录的负调控 8.6 Positive Control of Transcription ----Activator mediated regulation by protein-DNA binding IV. Global Regulation Mechanisms 8.7 Catabolite Repression ----Global control and the lac operon代谢分解物抑制 8.8 Other global control network 8.9 Quorum Sensing 群体感应