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清华大学:《生物化学》课程PPT教学课件(英文版)One difficulty in using entropy

process can occur spontaneously is that the entropy changes of chemical reactions are not readily measured. Furthermore, the criterion of sponta- neity given in equation 2 requires that both the entropy change of the surroundings and that of the system of interest be known. These difficul- ties are obviated by using different thermodynar function called the free energy, which is denoted by the symbol G (or F, in the older literature).
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